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Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91(PHOX) during myeloid differentiation

The IFN consensus sequence-binding protein (ICSBP; also referred to as IFN regulatory factor 8) is a transcription factor which is expressed in myeloid and B cells. In previous studies, we found that ICSBP activated transcription of the gene encoding gp91(PHOX) (the CYBB gene), a rate-limiting compo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhu, Chunliu, Lindsey, Stephan, Konieczna, Iwonna, Eklund, Elizabeth A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422644/
https://ncbi.nlm.nih.gov/pubmed/18089853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0807514
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