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Impaired Mouse Mammary Gland Growth and Development is Mediated by Melatonin and its MT1 G Protein-Coupled Receptor via Repression of ERα, Akt1, and Stat5

To determine if melatonin, via its MT(1) G protein-coupled receptor (GPCR), impacts mouse mammary gland development, we generated a mouse mammary tumor virus (MMTV)-MT1-Flag-mammary gland over-expressing (MT1-mOE) transgenic mouse. Increased expression of the MT(1)-Flag transgene was observed in the...

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Bibliografski detalji
Glavni autori: Xiang, Shulin, Mao, Lulu, Yuan, Lin, Duplessis, Tamika, Jones, Frank, Hoyle, Gary W., Frasch, Tripp, Dauchy, Robert, Blask, David E., Chakravarty, Geetika, Hill, Steven M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422609/
https://ncbi.nlm.nih.gov/pubmed/22582905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-079X.2012.01000.x
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