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Warburg Revisited: Regulation of Mitochondrial Metabolism by Voltage-Dependent Anion Channels in Cancer Cells

The bioenergetics of cancer cells is characterized by a high rate of aerobic glycolysis and suppression of mitochondrial metabolism (Warburg phenomenon). Mitochondrial metabolism requires inward and outward flux of hydrophilic metabolites, including ATP, ADP and respiratory substrates, through volta...

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Detalles Bibliográficos
Main Authors: Maldonado, Eduardo N., Lemasters, John J.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422523/
https://ncbi.nlm.nih.gov/pubmed/22700429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.192153
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