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p53 is required for the developmental restriction in Müller glial proliferation in mouse retina

Müller glia are normally mitotically quiescent cells, but in certain pathological states they can reenter the mitotic cell cycle. While several cell cycle regulators have been shown to be important in this process, a role for the tumor suppressor, p53, has not been demonstrated. Here, we investigate...

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Détails bibliographiques
Auteurs principaux: Ueki, Yumi, Karl, Mike O., Sudar, Samuel, Pollak, Julia, Taylor, Russell J., Loeffler, Kati, Wilken, Matthew S., Reardon, Sara, Reh, Thomas A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422417/
https://ncbi.nlm.nih.gov/pubmed/22777914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22377
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