Imaging Characteristics, Tissue Distribution, and Spread of a Novel Oncolytic Vaccinia Virus Carrying the Human Sodium Iodide Symporter

INTRODUCTION: Oncolytic viruses show promise for treating cancer. However, to assess therapy and potential toxicity, a noninvasive imaging modality is needed. This study aims to determine the in vivo biodistribution, and imaging and timing characteristics of a vaccinia virus, GLV-1h153, encoding the...

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Autori principali: Haddad, Dana, Chen, Chun-Hao, Carlin, Sean, Silberhumer, Gerd, Chen, Nanhai G., Zhang, Qian, Longo, Valerie, Carpenter, Susanne G., Mittra, Arjun, Carson, Joshua, Au, Joyce, Gonen, Mithat, Zanzonico, Pat B., Szalay, Aladar A., Fong, Yuman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422353/
https://ncbi.nlm.nih.gov/pubmed/22912675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041647
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