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Cell Death and Autophagy under Oxidative Stress: Roles of Poly(ADP-Ribose) Polymerases and Ca(2+)

On the cellular level, oxidative stress may cause various responses, including autophagy and cell death. All of these outcomes involve disturbed Ca(2+) signaling. Here we show that the nuclear enzymes poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 control cytosolic Ca(2+) shifts from extracellular...

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Detalhes bibliográficos
Main Authors: Wyrsch, Philippe, Blenn, Christian, Bader, Jessica, Althaus, Felix R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422003/
https://ncbi.nlm.nih.gov/pubmed/22751932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00437-12
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