The Effect of Bevacizumab on Human Malignant Melanoma Cells with Functional VEGF/VEGFR2 Autocrine and Intracrine Signaling Loops

Receptors for the angiogenic factor VEGF are expressed by tumor cancer cells including melanoma, although their functionality remains unclear. Paired human melanoma cell lines WM115 and WM239 were used to investigate differences in expression and functionality of VEGF and VEGFR2 in vitro and in vivo...

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Hlavní autoři: Adamcic, Una, Skowronski, Karolina, Peters, Craig, Morrison, Jodi, Coomber, Brenda L
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421957/
https://ncbi.nlm.nih.gov/pubmed/22904678
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