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VEGFR2 heterogeneity and response to anti-angiogenic low dose metronomic cyclophosphamide treatment
BACKGROUND: Targeting tumor vasculature is a strategy with great promise in the treatment of many cancers. However, anti-angiogenic reagents that target VEGF/VEGFR2 signaling have met with variable results clinically. Among the possible reasons for this may be heterogeneous expression of the target...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009683/ https://ncbi.nlm.nih.gov/pubmed/21159176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-683 |
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