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Efavirenz Pharmacokinetics in Cerebrospinal Fluid and Plasma over a 24-Hour Dosing Interval

We determined the pharmacokinetics of efavirenz in plasma and cerebrospinal fluid (CSF) over a 24-h dosing interval in a patient who had undergone a lumbar drain because of cryptococcal meningitis. Drug concentrations were determined by high-performance liquid chromatography-tandem mass spectrometry...

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Bibliografiske detaljer
Main Authors: Yilmaz, Aylin, Watson, Victoria, Dickinson, Laura, Back, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421893/
https://ncbi.nlm.nih.gov/pubmed/22687515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06311-11
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