Suppression of Transcription Factor Early Growth Response 1 Reduces Herpes Simplex Virus 1-Induced Corneal Disease in Mice

Herpes simplex virus 1 replication initiates angiogenesis and inflammation in the cornea. This can result in herpetic stromal keratitis (HSK), which is a leading cause of infection-induced corneal blindness. Host cellular factors mediate the progression of HSK, but little is known about these cellul...

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Bibliographic Details
Main Authors: Yao, Hui-Wen, Chen, Shih-Heng, Li, Ching, Tung, Yuk-Ying, Chen, Shun-Hua
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421710/
https://ncbi.nlm.nih.gov/pubmed/22647700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00505-12
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