Arenavirus Nucleoprotein Targets Interferon Regulatory Factor-Activating Kinase IKKε

Arenaviruses perturb innate antiviral defense by blocking induction of type I interferon (IFN) production. Accordingly, the arenavirus nucleoprotein (NP) was shown to block activation and nuclear translocation of interferon regulatory factor 3 (IRF3) in response to virus infection. Here, we sought t...

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Autores principales: Pythoud, Christelle, Rodrigo, W. W. Shanaka I., Pasqual, Giulia, Rothenberger, Sylvia, Martínez-Sobrido, Luis, de la Torre, Juan Carlos, Kunz, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421673/
https://ncbi.nlm.nih.gov/pubmed/22532683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00187-12
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