Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVS

Arenaviruses are important emerging human pathogens maintained by noncytolytic persistent infection in their rodent reservoir hosts. Despite high levels of viral replication, persistently infected carrier hosts show only mildly elevated levels of type I interferon (IFN-I). Accordingly, the arenaviru...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Pythoud, Christelle, Rothenberger, Sylvia, Martínez-Sobrido, Luis, de la Torre, Juan Carlos, Kunz, Stefan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474305/
https://ncbi.nlm.nih.gov/pubmed/25833049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00610-15
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