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Replication of Minute Virus of Mice in Murine Cells Is Facilitated by Virally Induced Depletion of p21
The DNA damage response to infection with minute virus of mice (MVM) leads to activated p53; however, p21 levels are reduced via a proteasome-mediated mechanism. This loss was sustained, as virus replicated in infected cells held at the G(2)/M border. Addition of the cyclin-dependent kinase (CDK) in...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421664/ https://ncbi.nlm.nih.gov/pubmed/22623787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00820-12 |
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