Equine Herpesvirus Type 4 UL56 and UL49.5 Proteins Downregulate Cell Surface Major Histocompatibility Complex Class I Expression Independently of Each Other

Major histocompatibility complex class I (MHC-I) molecules are critically important in the host defense against various pathogens through presentation of viral peptides to cytotoxic T lymphocytes (CTLs), a process resulting in the destruction of virus-infected cells. Herpesviruses interfere with CTL...

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Bibliographic Details
Main Authors: Said, Abdelrahman, Azab, Walid, Damiani, Armando, Osterrieder, Nikolaus
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421654/
https://ncbi.nlm.nih.gov/pubmed/22623773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00891-12
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