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Equine Herpesvirus Type 4 UL56 and UL49.5 Proteins Downregulate Cell Surface Major Histocompatibility Complex Class I Expression Independently of Each Other

Major histocompatibility complex class I (MHC-I) molecules are critically important in the host defense against various pathogens through presentation of viral peptides to cytotoxic T lymphocytes (CTLs), a process resulting in the destruction of virus-infected cells. Herpesviruses interfere with CTL...

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Detalhes bibliográficos
Main Authors: Said, Abdelrahman, Azab, Walid, Damiani, Armando, Osterrieder, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421654/
https://ncbi.nlm.nih.gov/pubmed/22623773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00891-12
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