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Identification and Characterization of Equine Herpesvirus Type 1 pUL56 and Its Role in Virus-Induced Downregulation of Major Histocompatibility Complex Class I

Major histocompatibility complex class I (MHC-I) molecules play an important role in host immunity to infection by presenting antigenic peptides to cytotoxic T lymphocytes (CTLs), which recognize and destroy virus-infected cells. Members of the Herpesviridae have developed multiple mechanisms to avo...

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Détails bibliographiques
Auteurs principaux: Ma, Guanggang, Feineis, Silke, Osterrieder, Nikolaus, Van de Walle, Gerlinde R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302497/
https://ncbi.nlm.nih.gov/pubmed/22278226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06994-11
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