Fluorescence Resonance Energy Transfer-Based Intracellular Assay for the Conformation of Hepatitis C Virus Drug Target NS5A

Nonstructural protein 5A (NS5A) is essential for hepatitis C virus (HCV) replication and assembly and is a critical drug target. Biochemical data suggest large parts of NS5A are unfolded as an isolated protein, but little is known about its folded state in the cell. We used fluorescence resonance en...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bhattacharya, Dipankar, Ansari, Israrul H., Mehle, Andrew, Striker, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421644/
https://ncbi.nlm.nih.gov/pubmed/22623794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00645-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados