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Different Biosynthetic Pathways to Fosfomycin in Pseudomonas syringae and Streptomyces Species

Fosfomycin is a wide-spectrum antibiotic that is used clinically to treat acute cystitis in the United States. The compound is produced by several strains of streptomycetes and pseudomonads. We sequenced the biosynthetic gene cluster responsible for fosfomycin production in Pseudomonas syringae PB-5...

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Bibliografiske detaljer
Main Authors: Kim, Seung Young, Ju, Kou-San, Metcalf, William W., Evans, Bradley S., Kuzuyama, Tomohisa, van der Donk, Wilfred A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421606/
https://ncbi.nlm.nih.gov/pubmed/22615277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06478-11
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