Identification of Disubstituted Sulfonamide Compounds as Specific Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation

Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) plays a central role in viral infection and persistence and is the basis for viral rebound after the cessation of therapy, as well as the elusiveness of a cure even after extended treatment. Therefore, there is an urgent need for the de...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cai, Dawei, Mills, Courtney, Yu, Wenquan, Yan, Ran, Aldrich, Carol E., Saputelli, Jeffry R., Mason, William S., Xu, Xiaodong, Guo, Ju-Tao, Block, Timothy M., Cuconati, Andrea, Guo, Haitao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421587/
https://ncbi.nlm.nih.gov/pubmed/22644022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00473-12
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