Hyperimmune Bovine Colostrum as a Low-Cost, Large-Scale Source of Antibodies with Broad Neutralizing Activity for HIV-1 Envelope with Potential Use in Microbicides

Bovine colostrum (first milk) contains very high concentrations of IgG, and on average 1 kg (500 g/liter) of IgG can be harvested from each immunized cow immediately after calving. We used a modified vaccination strategy together with established production systems from the dairy food industry for t...

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Detalhes bibliográficos
Main Authors: Kramski, Marit, Center, Rob J., Wheatley, Adam K., Jacobson, Jonathan C., Alexander, Marina R., Rawlin, Grant, Purcell, Damian F. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421555/
https://ncbi.nlm.nih.gov/pubmed/22664963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00453-12
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