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The inhibition of mitochondrial DNA polymerase gamma from animal cells by intercalating drugs.

DNA polymerase gamma from purified nuclei of EMT-6 cells (mice) seems to be identical to the mitochondrial DNA polymerase from the same source following several criteria. These two enzyme activities are strongly inhibited by ethidium bromide and acriflavin, while proflavin, acridine orange, daunomyc...

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Detalhes bibliográficos
Main Authors: Tarrago-Litvak, L, Viratelle, O, Darriet, D, Dalibart, R, Graves, P V, Litvak, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342153/
https://ncbi.nlm.nih.gov/pubmed/673850
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