The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk

Selective estrogen receptor modulators (SERMs) demonstrate differential endometrial cancer (EC) risk. While tamoxifen (TAM) use increases the risk of endometrial hyperplasia and malignancy, raloxifene (RAL) has neutral effects on the uterus. How TAM increases the risk of EC and why TAM and RAL diffe...

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Bibliografski detalji
Glavni autori: Williams-Brown, Marian Y., Salih, Sana M., Xu, Xia, Veenstra, Timothy D., Saeed, Muhammad, Theiler, Shaleen K., Diaz-Arrastia, Concepcion R., Salama, Salama A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421458/
https://ncbi.nlm.nih.gov/pubmed/21600284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.05.001
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