The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk

Selective estrogen receptor modulators (SERMs) demonstrate differential endometrial cancer (EC) risk. While tamoxifen (TAM) use increases the risk of endometrial hyperplasia and malignancy, raloxifene (RAL) has neutral effects on the uterus. How TAM increases the risk of EC and why TAM and RAL diffe...

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Detaylı Bibliyografya
Asıl Yazarlar: Williams-Brown, Marian Y., Salih, Sana M., Xu, Xia, Veenstra, Timothy D., Saeed, Muhammad, Theiler, Shaleen K., Diaz-Arrastia, Concepcion R., Salama, Salama A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421458/
https://ncbi.nlm.nih.gov/pubmed/21600284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.05.001
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