The chemical synthesis of the anticodon loop of an eukaryotic initiator tRNA containing the hypermodified nucleoside N6-/N-threonylcarbonyl/-adenosine/t6A/1.

In this work, the first example of chemical synthesis of oligoribonucleotide containing the hypermodified nucleoside N6-/N-threonylcarbonyl/-adenosine /t6A/ is presented. Synthesis of the heptamer C-C-C-A-U-t6A-A IX, the sequence of which is related to the anticodon loop of the initiator tRNA from y...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Adamiak, R W, Biała, E, Grześkowiak, K, Kierzek, R, Kraszewski, A, Markiewicz, W T, Okupniak, J, Stawiński, J, Wiewiórowski, M
Format: Artigo
Language:Inglês
Published: Oxford University Press 1978
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/673839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/5.6.1889
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