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Scaling metagenome sequence assembly with probabilistic de Bruijn graphs
Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for de novo assembly of short-read shotgun sequencing data from these complex populations are an increasingly large practical barrier. Here we introduce a memory-effi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421212/ https://ncbi.nlm.nih.gov/pubmed/22847406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121464109 |
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