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Scaling metagenome sequence assembly with probabilistic de Bruijn graphs

Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for de novo assembly of short-read shotgun sequencing data from these complex populations are an increasingly large practical barrier. Here we introduce a memory-effi...

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Detalhes bibliográficos
Main Authors: Pell, Jason, Hintze, Arend, Canino-Koning, Rosangela, Howe, Adina, Tiedje, James M., Brown, C. Titus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421212/
https://ncbi.nlm.nih.gov/pubmed/22847406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121464109
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