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Structure of androcam supports specialized interactions with myosin VI

Androcam replaces calmodulin as a tissue-specific myosin VI light chain on the actin cones that mediate D. melanogaster spermatid individualization. We show that the androcam structure and its binding to the myosin VI structural (Insert 2) and regulatory (IQ) light chain sites are distinct from thos...

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Autores principales: Joshi, Mehul K., Moran, Sean, Beckingham, Kathleen M., MacKenzie, Kevin R.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421203/
https://ncbi.nlm.nih.gov/pubmed/22851764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209730109
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