No evidence for additional blood–brain barrier P-glycoprotein dysfunction in Alzheimer's disease patients with microbleeds

Decreased blood–brain barrier P-glycoprotein (Pgp) function has been shown in Alzheimer's disease (AD) patients using positron emission tomography (PET) with the radiotracer (R)-[(11)C]verapamil. Decreased Pgp function has also been hypothesized to promote cerebral amyloid angiopathy (CAA) deve...

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Detalhes bibliográficos
Main Authors: van Assema, Daniëlle ME, Goos, Jeroen DC, van der Flier, Wiesje M, Lubberink, Mark, Boellaard, Ronald, Windhorst, Albert D, Scheltens, Philip, Lammertsma, Adriaan A, van Berckel, Bart NM
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421102/
https://ncbi.nlm.nih.gov/pubmed/22588188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.64
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