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Cervical Cancers Require the Continuous Expression of the Human Papillomavirus Type 16 E7 Oncoprotein Even in the Presence of the Viral E6 Oncoprotein

High-risk human papillomaviruses (HPV), such as HPV-16, are etiologic agents of a variety of anogenital and oral malignancies, including nearly all cases of cervical cancer. Cervical cancers arising in transgenic mice that express HPV-16 E7 in an inducible manner require the continuous expression of...

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Detalhes bibliográficos
Main Authors: Jabbar, Sean F., Park, Soyeong, Schweizer, Johannes, Berard-Bergery, Marthe, Pitot, Henry C., Lee, Denis, Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421037/
https://ncbi.nlm.nih.gov/pubmed/22700879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3085
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