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ARF6-Dependent Regulation of P2Y Receptor Traffic and Function in Human Platelets

Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors, the P2Y(1) and P2Y(12) purinoceptors. Recently, we demonstrated that P2Y(1) and P2Y(12) purinoceptor activities are rapidly and reversibly modulated in human pla...

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Detalhes bibliográficos
Main Authors: Kanamarlapudi, Venkateswarlu, Owens, Sian E., Saha, Keya, Pope, Robert J., Mundell, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420901/
https://ncbi.nlm.nih.gov/pubmed/22916275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043532
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