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TRPV1 activation is not an all-or-none event: TRPV1 partial agonism/antagonism and its regulatory modulation

TRPV1 has emerged as a promising therapeutic target for pain as well as a broad range of other conditions such as asthma or urge incontinence. The identification of resiniferatoxin as an ultrapotent ligand partially able to dissect the acute activation of TRPV1 from subsequent desensitization and th...

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Autors principals: Blumberg, Peter M., Pearce, Larry V., Lee, Jeewoo
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420352/
https://ncbi.nlm.nih.gov/pubmed/21671879
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