Thymus-autonomous T cell development in the absence of progenitor import

Thymus function is thought to depend on a steady supply of T cell progenitors from the bone marrow. The notion that the thymus lacks progenitors with self-renewal capacity is based on thymus transplantation experiments in which host-derived thymocytes replaced thymus-resident cells within 4 wk. Thym...

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Detalhes bibliográficos
Main Authors: Martins, Vera C., Ruggiero, Eliana, Schlenner, Susan M., Madan, Vikas, Schmidt, Manfred, Fink, Pamela J., von Kalle, Christof, Rodewald, Hans-Reimer
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420332/
https://ncbi.nlm.nih.gov/pubmed/22778389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120846
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