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A quantitative quasispecies theory-based model of virus escape mutation under immune selection
Viral infections involve a complex interplay of the immune response and escape mutation of the virus quasispecies inside a single host. Although fundamental aspects of such a balance of mutation and selection pressure have been established by the quasispecies theory decades ago, its implications hav...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3420195/ https://ncbi.nlm.nih.gov/pubmed/22826258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117201109 |
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