Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion

The homotypic fusion of endoplasmic reticulum (ER) membranes is mediated by atlastin (ATL), which consists of an N-terminal cytosolic domain containing a GTPase module and a three-helix bundle followed by two transmembrane (TM) segments and a C-terminal tail (CT). Fusion depends on a GTP hydrolysis-...

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Detalhes bibliográficos
Main Authors: Liu, Tina Y., Bian, Xin, Sun, Sha, Hu, Xiaoyu, Klemm, Robin W., Prinz, William A., Rapoport, Tom A., Hu, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420179/
https://ncbi.nlm.nih.gov/pubmed/22802620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208385109
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