A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression

By analyzing public data sets of gene expression in human breast cancers we observed that increased levels of transcripts encoding the planar cell polarity (PCP) proteins SCRIB and VANGL1 correlate with increased risk of patient relapse. Experimentally, we found that reducing expression of SCRIB by...

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Bibliografiske detaljer
Main Authors:	Anastas, J N, Biechele, T L, Robitaille, M, Muster, J, Allison, K H, Angers, S, Moon, R T
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2012
Fag:	Original Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3419983/ https://ncbi.nlm.nih.gov/pubmed/22179838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.528
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A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression

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