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Chronic and intermittent hypoxia differentially regulate left ventricular inflammatory and extracellular matrix responses

We evaluated the left ventricle (LV) response to hypoxia by comparing male Sprague Dawley rats exposed for 7 days to normoxia (control; n=18), chronic sustained hypoxia (CSH; n=12) and chronic intermittent hypoxia (CIH; n=12). Out of the 168 inflammatory, extracellular matrix and adhesion molecule g...

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Bibliographic Details
Main Authors: Ramirez, Trevi A, Jourdan-Le Saux, Claude, Joy, Anne, Zhang, Jianhua, Dai, Qiuxia, Mifflin, Steve, Lindsey, Merry L
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419973/
https://ncbi.nlm.nih.gov/pubmed/22495609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2012.32
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