Phase I dose-escalation study of aflibercept in combination with docetaxel and cisplatin in patients with advanced solid tumours

BACKGROUND: This phase I cohort study investigated aflibercept (vascular endothelial growth factor (VEGF) trap) plus docetaxel and cisplatin in patients with advanced solid tumours. METHODS: Patients received intravenous aflibercept 4, 5, or 6 mg kg(−1) with docetaxel and cisplatin (75 mg m(−2) each...

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Detalhes bibliográficos
Main Authors: Freyer, G, Isambert, N, You, B, Zanetta, S, Falandry, C, Favier, L, Trillet-Lenoir, V, Assadourian, S, Soussan-Lazard, K, Ziti-Ljajic, S, Fumoleau, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419955/
https://ncbi.nlm.nih.gov/pubmed/22790797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.304
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