Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning

DP1, a dimerization partner protein of the transcription factor E2F, is known to inhibit Wnt/β-catenin signalling along with E2F, although the function of DP1 itself was not well characterized. Here, we present a novel dual regulatory mechanism of Wnt/β-catenin signalling by DP1 independent from E2F...

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Hlavní autoři: Kim, Wan-tae, Kim, Hyunjoon, Katanaev, Vladimir L, Joon Lee, Seung, Ishitani, Tohru, Cha, Boksik, Han, Jin-Kwan, Jho, Eek-hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419924/
https://ncbi.nlm.nih.gov/pubmed/22773187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.181
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