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C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules

The human disease Hermansky-Pudlak syndrome results from defective biogenesis of lysosome-related organelles (LROs) and can be caused by mutations in subunits of the BLOC-1 complex. Here we show that C. elegans glo-2 and snpn-1, despite relatively low levels of amino acid identity, encode Pallidin a...

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Detalhes bibliográficos
Main Authors: Hermann, Greg J., Scavarda, Emily, Weis, Allison M., Saxton, Daniel S., Thomas, Laura L., Salesky, Rebecca, Somhegyi, Hannah, Curtin, Thomas P., Barrett, Alec, Foster, Olivia K., Vine, Annalise, Erlich, Katherine, Kwan, Elizabeth, Rabbitts, Beverley M., Warren, Kaila
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419718/
https://ncbi.nlm.nih.gov/pubmed/22916203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043043
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