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C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules
The human disease Hermansky-Pudlak syndrome results from defective biogenesis of lysosome-related organelles (LROs) and can be caused by mutations in subunits of the BLOC-1 complex. Here we show that C. elegans glo-2 and snpn-1, despite relatively low levels of amino acid identity, encode Pallidin a...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419718/ https://ncbi.nlm.nih.gov/pubmed/22916203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043043 |
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