glo-3, a Novel Caenorhabditis elegans Gene, Is Required for Lysosome-Related Organelle Biogenesis

Gut granules are specialized lysosome-related organelles that act as sites of fat storage in Caenorhabditis elegans intestinal cells. We identified mutations in a gene, glo-3, that functions in the formation of embryonic gut granules. Some glo-3(−) alleles displayed a complete loss of embryonic gut...

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Bibliografiske detaljer
Main Authors: Rabbitts, Beverley M., Ciotti, Marcela K., Miller, Natalie E., Kramer, Maxwell, Lawrenson, Andrea L., Levitte, Steven, Kremer, Susan, Kwan, Elizabeth, Weis, Allison M., Hermann, Greg J.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2008
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567386/
https://ncbi.nlm.nih.gov/pubmed/18780725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.093534
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