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Effect of DNA on poly (ADP-ribose) glycohydrolase and the degradation of histone H1-poly (ADP-ribose) complex from HeLa cell nuclei.

A poly(ADP-ribose)-H1 histone complex has been isolated from HeLa cell nuclei incubated with NAD. The rate of poly(ADP-ribose) glycohydrolase catalyzed hydrolysis of the polymer in the complex is only 1/9 that of free poly(ADP-ribose), indicating that the polymer is in a protected environment within...

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Detalhes bibliográficos
Main Authors: Stone, P R, Lorimer, W S, Ranchalis, J, Danley, M, Kidwell, W R
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC341969/
https://ncbi.nlm.nih.gov/pubmed/643606
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