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Protease-Activated Receptor 2 Mediates Mucus Secretion in the Airway Submucosal Gland

Protease-activated receptor 2 (PAR2), a G protein-coupled receptor expressed in airway epithelia and smooth muscle, plays an important role in airway inflammation. In this study, we demonstrated that activation of PAR2 induces mucus secretion from the human airway gland and examined the underlying m...

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Autori principali: Lee, Hyun Jae, Yang, Yu-Mi, Kim, Kyubo, Shin, Dong Min, Yoon, Joo-Heon, Cho, Hyung-Ju, Choi, Jae Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419645/
https://ncbi.nlm.nih.gov/pubmed/22916223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043188
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