Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

To identify novel late-onset Alzheimer disease (LOAD) risk genes, we have analyzed Amish populations of Ohio and Indiana. We performed genome-wide SNP linkage and association studies on 798 individuals (109 with LOAD). We tested association using the Modified Quasi-Likelihood Score (MQLS) test and a...

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Hlavní autoři: Cummings, Anna C., Jiang, Lan, Velez Edwards, Digna R., McCauley, Jacob L., Laux, Renee, McFarland, Lynne L., Fuzzell, Denise, Knebusch, Clare, Caywood, Laura, Reinhart-Mercer, Lori, Nations, Laura, Gilbert, John R., Konidari, Ioanna, Tramontana, Michael, Cuccaro, Michael L., Scott, William K., Pericak-Vance, Margaret A., Haines, Jonathan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419486/
https://ncbi.nlm.nih.gov/pubmed/22881374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00721.x
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