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Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

A mild, versatile and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes has been developed based on a copper-catalyzed oxidative difunctionalization strategy. This methodology provides access to a variety of classes of synthetically useful CF(3)-containing building b...

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Autori principali: Zhu, Rong, Buchwald, Stephen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419474/
https://ncbi.nlm.nih.gov/pubmed/22804336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja305840g
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