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CYP2C19 polymorphism affects single-dose pharmacokinetics of oral pantoprazole in healthy volunteers
OBJECTIVES: Pantoprazole is metabolized by cytochrome P450 2 C19, which shows genetic polymorphism. The effect of CYP2C19 polymorphism on single-dose pharmacokinetics of oral pantoprazole in healthy volunteers was evaluated. METHODS: Pantoprazole pharmacokinetics was determined in 32 healthy volunte...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419350/ https://ncbi.nlm.nih.gov/pubmed/22418828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-012-1252-3 |
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