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Plasmin Is the Major Protease Responsible for Processing PDGF-C in the Vitreous of Patients with Proliferative Vitreoretinopathy

PURPOSE: Proliferative vitreoretinopathy (PVR) is the primary cause of failure of retinal reattachment surgery. Growth factors such as platelet-derived growth factor (PDGF) are strongly associated with PVR. Of the five PDGF family members, PDGF-C predominates in the vitreous of experimental and clin...

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Detalhes bibliográficos
Main Authors: Lei, Hetian, Velez, Gisela, Hovland, Peter, Hirose, Tatsuo, Kazlauskas, Andrius
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419256/
https://ncbi.nlm.nih.gov/pubmed/18172073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0776
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