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Positive Selection on the Osteoarthritis-Risk and Decreased-Height Associated Variants at the GDF5 Gene in East Asians

GDF5 is a member of the bone morphogenetic protein (BMP) gene family, and plays an important role in the development of the skeletal system. Variants of the gene are associated with osteoarthritis and height in some human populations. Here, we resequenced the gene in individuals from four geographic...

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Sonraí Bibleagrafaíochta
Main Authors: Wu, Dong-Dong, Li, Gui-Mei, Jin, Wei, Li, Yan, Zhang, Ya-Ping
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419199/
https://ncbi.nlm.nih.gov/pubmed/22905146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042553
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