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Positive Selection on the Osteoarthritis-Risk and Decreased-Height Associated Variants at the GDF5 Gene in East Asians

GDF5 is a member of the bone morphogenetic protein (BMP) gene family, and plays an important role in the development of the skeletal system. Variants of the gene are associated with osteoarthritis and height in some human populations. Here, we resequenced the gene in individuals from four geographic...

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Detalhes bibliográficos
Main Authors: Wu, Dong-Dong, Li, Gui-Mei, Jin, Wei, Li, Yan, Zhang, Ya-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419199/
https://ncbi.nlm.nih.gov/pubmed/22905146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042553
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