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Identification of Protective Pneumococcal T(H)17 Antigens from the Soluble Fraction of a Killed Whole Cell Vaccine
Mucosal or parenteral immunization with a killed unencapsulated pneumococcal whole cell antigen (WCA) with an adjuvant protects mice from colonization by a T(H)17 CD4+ cell-mediated mechanism. Using preparative SDS gels, we separated the soluble proteins that compose the WCA in order to identify fra...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419164/ https://ncbi.nlm.nih.gov/pubmed/22905267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043445 |
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