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Identification of Protective Pneumococcal T(H)17 Antigens from the Soluble Fraction of a Killed Whole Cell Vaccine

Mucosal or parenteral immunization with a killed unencapsulated pneumococcal whole cell antigen (WCA) with an adjuvant protects mice from colonization by a T(H)17 CD4+ cell-mediated mechanism. Using preparative SDS gels, we separated the soluble proteins that compose the WCA in order to identify fra...

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Detalhes bibliográficos
Main Authors: Moffitt, Kristin L., Malley, Richard, Lu, Ying-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419164/
https://ncbi.nlm.nih.gov/pubmed/22905267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043445
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