Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1

BACKGROUND: Transforming growth factor-β1 (TGF-β1) is an important regulator of cell migration and plays a role in the scarring response in injured brain. It is also reported that 5-lipoxygenase (5-LOX) and its products, cysteinyl leukotrienes (CysLTs, namely LTC(4), LTD(4) and LTE(4)), as well as c...

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Autores principales: Huang, Xue-Qin, Zhang, Xia-Yan, Wang, Xiao-Rong, Yu, Shu-Ying, Fang, San-Hua, Lu, Yun-Bi, Zhang, Wei-Ping, Wei, Er-Qing
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419068/
https://ncbi.nlm.nih.gov/pubmed/22734808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-145
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