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Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin

Epileptic seizures are a common feature associated with inherited mitochondrial diseases. This study investigated the role of mitochondrial oxidative stress in epilepsy resulting from mitochondrial dysfunction using cross-bred mutant mice lacking mitochondrial manganese superoxide dismutase (MnSOD o...

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Hlavní autoři: Liang, Li-Ping, Waldbaum, Simon, Rowley, Shane, Huang, Ting-Ting, Day, Brian J., Patel, Manisha
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418969/
https://ncbi.nlm.nih.gov/pubmed/22200564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.12.025
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